Teduglutide CAS: 197922-42-2 Ntugharị ALX 0600 Gattex

Ọrụ:
Teduglutide, nke a maara na bekee dị ka Teduglutide, bụ ihe analọg nke glucagon-dị ka peptide 2 (GLP-2), hormone na-eme n'ọdịdị nke na-ebelata mkpofu afọ na nzuzo ma na-achịkwa uto, mmụba, na nrụzi nke mkpụrụ ndụ n'ime eriri afọ.Ọgwụ na-abawanye ọnụ ọgụgụ nke mkpụrụ ndụ ndị a, nke na-abawanye nnabata na eriri afọ ma belata afọ ọsịsa.
Nkwadebe:
Nhazi nke mgbanaka nwere akụkụ ise nwere njikọ chiri anya na amino acid ziri ezi nke Asp ma ọ bụ Asn, na Gly bụ usoro mgbanaka kacha dị mfe etolite mgbe ejikọtara Gly tupu Asp n'ihi enweghị otu nchebe na obere mgbochi dị n'akụkụ. yinye.Ya mere, ọ bụ ihe a na-apụghị izere ezere na usoro njikọ usoro ga-eme ka amino acids N-terminal nke Teduchemicalbook lupeptide ghọọ mgbanaka nwere akụkụ ise na usoro nhazi, si otú a na-ebelata ịdị ọcha.Ya mere, iji dozie nsogbu nbibi nke Asp-Gly, a na-ebu ụzọ mepụta mpempe akwụkwọ echekwara nke ọma na nhazi nke egosiri na SEQIDNO: 2 site na ijikọta iberibe.Iberibe ahụ echekwara nke ọma bụ nke mbụ ~ anọ amino acid nke N-terminal of tidulutide, gụnyere nhazi Asp-Gly, wee sachaa iberibe ahụ echekwara nke ọma.Iberibe ahụ e kpuchiri ekpuchi nke ọma bụ nke siri ike jikọtara ya na peptide resin peptide nwere nhazi nke egosiri na SEQIDNO:12, na nke ikpeazụ bụ nke e mere iji nweta tidurotide.