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Argipressin CAS: 113-79-1 AVP BETA-HYPOPHAMINE

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  • Ọ BỤGHỊ:113-79-1
  • Aha:Argipressin
  • Usoro kemịkalụ:C46H65N15O12S2
  • njupụta:1.59±0.1 g/cm3 (buru amụma)
  • Fp:113 ℃
  • nchekwa okpomọkụ.:2-8 Celsius C
  • pka:9.90±0.15 (buru amụma)
  • PH:3.5
  • ụdị:ntụ ntụ
  • Ọnụ ọgụgụ nke molar:1084.24
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    [Arg8] - A na-eji ngwọta Vasopressin dị ka antigen maka ịkwadebe antisera preadsorbed maka immunocytochemistry.Ejiri ngwaahịa a na omenala L6 cell nke C5 subclone maka ọmụmụ ihe dị iche.

    N'ihi na ọ kwụsiri ike, a na-ahọrọ desmopressin maka ọgwụgwọ karịsịa ma ọ bụrụ na achọghị mmetụta pressor.Isi ihe na-egosi ọgwụgwọ bụ isi ọrịa shuga insipidus, ọrịa na-akpata mgbe mbelata ADH secretion na nke a na-eji polydipsia, polyuria, na akpịrị ịkpọ nkụ.A na-ejikwa Desmopressin iji belata enuresis nke mbụ nke abalị, ma ọ bụ akwa akwa, na ụmụaka.Ọ bara uru na ndị nwere hemophilia A dị nro ma ọ bụ nwere ụfọdụ ụdị ọrịa von Willebrand, nke ihe von Willebrand dị na ọkwa dị ala.N'ọnọdụ ndị a, a na-enye desmopressin mgbe ọbara ọgbụgba dị ukwuu na-eme ma ọ bụ tupu ịwa ahụ iji nyere aka belata ọbara ọgbụgba na-apụtaghị ìhè site na ịba ụba nke coagulation ihe.Mmetụta ọjọọ nke desmopressin nwere ike ime bụ ịṅụbiga mmanya ókè ma ọ bụrụ na ewere ya nke ukwuu.
    Ndị na-emegide ADH, gụnyere analogues na-abụghị peptide nke enwere ike were ọnụ, emepụtara ya na nkọwapụta maka ụdị nnabata ọ bụla.N'ọdịnihu, ndị na-egbochi ndị na-anabata V1 nwere ike ịba uru n'ịgwọ ọbara mgbali elu, na ndị na-egbochi ndị na-anabata V2 nwere ike ịba uru na ọnọdụ ọ bụla nke oke mmiri na-ejide ma ọ bụ hyponatremia, nke ruo ugbu a enweghị ọgwụgwọ ọgwụgwọ na-eju afọ.

     

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